Rungia pectinata (Linn.) Nees: A Review of Phytochemical Analysis and Pharmacological Activities

Rungia pectinata L. is an herbaceous weed traditionally used for many years for various disease conditions. Nevertheless, these indigenous medical practices are frequently regarded as self-limiting, necessitating a thorough examination of their purported benefits. This review aims to consolidate exi...

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Main Authors: Forid, Md. Shaekh, Azuri, Muhammad Saupi bin, Wan Ishak, Wan Maznah, Hossain, Md. Sanower
Format: UMS Journal (OJS)
Language:eng
Published: Universitas Muhammadiyah Surakarta 2024
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Online Access:https://journals.ums.ac.id/index.php/pharmacon/article/view/23596
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author Forid, Md. Shaekh
Azuri, Muhammad Saupi bin
Wan Ishak, Wan Maznah
Hossain, Md. Sanower
author_facet Forid, Md. Shaekh
Azuri, Muhammad Saupi bin
Wan Ishak, Wan Maznah
Hossain, Md. Sanower
author_sort Forid, Md. Shaekh
collection OJS
description Rungia pectinata L. is an herbaceous weed traditionally used for many years for various disease conditions. Nevertheless, these indigenous medical practices are frequently regarded as self-limiting, necessitating a thorough examination of their purported benefits. This review aims to consolidate existing scientific insights and identify domains requiring additional research. The literature was searched using the keyword "Rungia pectinata" OR "Comb Rungia" in well-known scientific databases, including PubMed, Web of Science, and Scopus, and relevant papers were selected for this review. The leaf juice is used as a cooling agent and to treat smallpox in children, reducing pain and swelling. A paste made from the fresh leaves blended with castor oil can heal tinea capitis, a scaly fungoid scalp infection. This plant has a rich tradition of use in treating different disease conditions, such as hepatitis, acute conjunctivitis, children's dyspepsia, dysentery, and lymphoid tuberculosis. Additionally, it exhibits diverse pharmacological activities like antipyretic, anti-inflammatory, diuretic, analgesic, antifungal, and antibacterial effects. This study found that it has secondary metabolites, such as amino acids, glycosides, phenolics, terpenes, phytosterols, tannins, flavonoids, and carbohydrates. Additionally, a total of 38 isolated compounds were identified in essential oils, with the dominant compounds being trans-phytol, hexahydrofarnesyl acetone, and isophytol. However, the phytochemical compositions varied depending on the type of extraction process. R. pectinata presents a promising avenue for medicinal exploration, deeply rooted in traditional practices. This review underscores the need for a more thorough investigation into its diverse therapeutic applications and encourages further research to unlock the plant's full potential.
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spelling oai:ojs2.journals.ums.ac.id:article-23596 Rungia pectinata (Linn.) Nees: A Review of Phytochemical Analysis and Pharmacological Activities Forid, Md. Shaekh Azuri, Muhammad Saupi bin Wan Ishak, Wan Maznah Hossain, Md. Sanower anti-inflammatory; Rungia pectinata; traditional medicine; medicinal plant; phytochemical analysis; therapeutic potential Rungia pectinata L. is an herbaceous weed traditionally used for many years for various disease conditions. Nevertheless, these indigenous medical practices are frequently regarded as self-limiting, necessitating a thorough examination of their purported benefits. This review aims to consolidate existing scientific insights and identify domains requiring additional research. The literature was searched using the keyword "Rungia pectinata" OR "Comb Rungia" in well-known scientific databases, including PubMed, Web of Science, and Scopus, and relevant papers were selected for this review. The leaf juice is used as a cooling agent and to treat smallpox in children, reducing pain and swelling. A paste made from the fresh leaves blended with castor oil can heal tinea capitis, a scaly fungoid scalp infection. This plant has a rich tradition of use in treating different disease conditions, such as hepatitis, acute conjunctivitis, children's dyspepsia, dysentery, and lymphoid tuberculosis. Additionally, it exhibits diverse pharmacological activities like antipyretic, anti-inflammatory, diuretic, analgesic, antifungal, and antibacterial effects. This study found that it has secondary metabolites, such as amino acids, glycosides, phenolics, terpenes, phytosterols, tannins, flavonoids, and carbohydrates. Additionally, a total of 38 isolated compounds were identified in essential oils, with the dominant compounds being trans-phytol, hexahydrofarnesyl acetone, and isophytol. However, the phytochemical compositions varied depending on the type of extraction process. R. pectinata presents a promising avenue for medicinal exploration, deeply rooted in traditional practices. This review underscores the need for a more thorough investigation into its diverse therapeutic applications and encourages further research to unlock the plant's full potential. Universitas Muhammadiyah Surakarta 2024-04-08 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journals.ums.ac.id/index.php/pharmacon/article/view/23596 10.23917/pharmacon.v21i0.23596 Pharmacon: Jurnal Farmasi Indonesia; Vol 21, Special Issue 1, 2024; 104-110 2685-5062 1411-4283 eng https://journals.ums.ac.id/index.php/pharmacon/article/view/23596/8970 Copyright (c) 2024 Pharmacon: Jurnal Farmasi Indonesia https://creativecommons.org/licenses/by-nc-sa/4.0
spellingShingle anti-inflammatory; Rungia pectinata; traditional medicine; medicinal plant; phytochemical analysis; therapeutic potential
Forid, Md. Shaekh
Azuri, Muhammad Saupi bin
Wan Ishak, Wan Maznah
Hossain, Md. Sanower
Rungia pectinata (Linn.) Nees: A Review of Phytochemical Analysis and Pharmacological Activities
title Rungia pectinata (Linn.) Nees: A Review of Phytochemical Analysis and Pharmacological Activities
title_full Rungia pectinata (Linn.) Nees: A Review of Phytochemical Analysis and Pharmacological Activities
title_fullStr Rungia pectinata (Linn.) Nees: A Review of Phytochemical Analysis and Pharmacological Activities
title_full_unstemmed Rungia pectinata (Linn.) Nees: A Review of Phytochemical Analysis and Pharmacological Activities
title_short Rungia pectinata (Linn.) Nees: A Review of Phytochemical Analysis and Pharmacological Activities
title_sort rungia pectinata linn nees a review of phytochemical analysis and pharmacological activities
topic anti-inflammatory; Rungia pectinata; traditional medicine; medicinal plant; phytochemical analysis; therapeutic potential
topic_facet anti-inflammatory; Rungia pectinata; traditional medicine; medicinal plant; phytochemical analysis; therapeutic potential
url https://journals.ums.ac.id/index.php/pharmacon/article/view/23596
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