Cytotoxic Effects of Plant Bioactive Compounds on T47d Breast Cancer Cells Line: A Review
The continuous cell line known as T47D cells originates from the isolation of epithelial cells from the ductal breast tissue of a 54-year-old woman with metastatic breast cancer. Numerous plant species have been employed in alternative anti-breast cancer therapy, showing advancements in recent years...
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| Format: | UMS Journal (OJS) |
| Language: | eng |
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Universitas Muhammadiyah Surakarta
2024
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| Online Access: | https://journals.ums.ac.id/index.php/bioeksperimen/article/view/23534 |
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| _version_ | 1805338157580812288 |
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| author | Firmansyah, Tio Saraswati, Utami Ilham, Kurniadi Jannatan, Robby maliza, rita |
| author_facet | Firmansyah, Tio Saraswati, Utami Ilham, Kurniadi Jannatan, Robby maliza, rita |
| author_sort | Firmansyah, Tio |
| collection | OJS |
| description | The continuous cell line known as T47D cells originates from the isolation of epithelial cells from the ductal breast tissue of a 54-year-old woman with metastatic breast cancer. Numerous plant species have been employed in alternative anti-breast cancer therapy, showing advancements in recent years. The aim of this systematic review is to assess the potential bioactive compounds from herbal plant extracts and analyze the effects of herbal plants on T47D breast cancer cells. This research employs a systematic approach to gather articles, encompassing related research questions, chosen databases, keyword selection, inclusion and exclusion criteria, as well as outcomes and conclusions regarding the collected articles. From the reviewed articles, several plants exhibit anti-breast cancer activity on T47D cell lines, namely Calamintha incana, Sterculia quadrifida, Psidium guajava, Uncaria nervosa, Syzygium aqueum, Capsicum annum, Bauhinia scandens, Lansium domesticum, and Garcinia cowa due to their content of bioactive compounds such as triterpenoids, alkaloids, phenolics, flavonoids, saponins, and tannins. These bioactive compounds from the plants exert significant influence on cell cycle, proliferation, fatty acid synthesis, and apoptosis of cancer cells. |
| format | UMS Journal (OJS) |
| id | oai:ojs2.journals.ums.ac.id:article-23534 |
| institution | Universitas Muhammadiyah Surakarta |
| language | eng |
| publishDate | 2024 |
| publisher | Universitas Muhammadiyah Surakarta |
| record_format | ojs |
| spelling | oai:ojs2.journals.ums.ac.id:article-23534 Cytotoxic Effects of Plant Bioactive Compounds on T47d Breast Cancer Cells Line: A Review Firmansyah, Tio Saraswati, Utami Ilham, Kurniadi Jannatan, Robby maliza, rita The continuous cell line known as T47D cells originates from the isolation of epithelial cells from the ductal breast tissue of a 54-year-old woman with metastatic breast cancer. Numerous plant species have been employed in alternative anti-breast cancer therapy, showing advancements in recent years. The aim of this systematic review is to assess the potential bioactive compounds from herbal plant extracts and analyze the effects of herbal plants on T47D breast cancer cells. This research employs a systematic approach to gather articles, encompassing related research questions, chosen databases, keyword selection, inclusion and exclusion criteria, as well as outcomes and conclusions regarding the collected articles. From the reviewed articles, several plants exhibit anti-breast cancer activity on T47D cell lines, namely Calamintha incana, Sterculia quadrifida, Psidium guajava, Uncaria nervosa, Syzygium aqueum, Capsicum annum, Bauhinia scandens, Lansium domesticum, and Garcinia cowa due to their content of bioactive compounds such as triterpenoids, alkaloids, phenolics, flavonoids, saponins, and tannins. These bioactive compounds from the plants exert significant influence on cell cycle, proliferation, fatty acid synthesis, and apoptosis of cancer cells. Universitas Muhammadiyah Surakarta Bioactive compounds, Breast Cancer, MTT assay, Review, T4D7 2024-05-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journals.ums.ac.id/index.php/bioeksperimen/article/view/23534 10.23917/bioeksperimen.v10i1.23534 Bioeksperimen: Jurnal Penelitian Biologi; Vol 10, No 1: March 2024; 11-22 Bioeksperimen: Jurnal Penelitian Biologi; Vol 10, No 1: March 2024; 11-22 2527-2799 2460-1365 eng https://journals.ums.ac.id/index.php/bioeksperimen/article/view/23534/8992 https://journals.ums.ac.id/index.php/bioeksperimen/article/downloadSuppFile/23534/6119 Copyright (c) 2024 Bioeksperimen: Jurnal Penelitian Biologi http://creativecommons.org/licenses/by-sa/4.0 |
| spellingShingle | Firmansyah, Tio Saraswati, Utami Ilham, Kurniadi Jannatan, Robby maliza, rita Cytotoxic Effects of Plant Bioactive Compounds on T47d Breast Cancer Cells Line: A Review |
| title | Cytotoxic Effects of Plant Bioactive Compounds on T47d Breast Cancer Cells Line: A Review |
| title_full | Cytotoxic Effects of Plant Bioactive Compounds on T47d Breast Cancer Cells Line: A Review |
| title_fullStr | Cytotoxic Effects of Plant Bioactive Compounds on T47d Breast Cancer Cells Line: A Review |
| title_full_unstemmed | Cytotoxic Effects of Plant Bioactive Compounds on T47d Breast Cancer Cells Line: A Review |
| title_short | Cytotoxic Effects of Plant Bioactive Compounds on T47d Breast Cancer Cells Line: A Review |
| title_sort | cytotoxic effects of plant bioactive compounds on t47d breast cancer cells line a review |
| url | https://journals.ums.ac.id/index.php/bioeksperimen/article/view/23534 |
| work_keys_str_mv | AT firmansyahtio cytotoxiceffectsofplantbioactivecompoundsont47dbreastcancercellslineareview AT saraswatiutami cytotoxiceffectsofplantbioactivecompoundsont47dbreastcancercellslineareview AT ilhamkurniadi cytotoxiceffectsofplantbioactivecompoundsont47dbreastcancercellslineareview AT jannatanrobby cytotoxiceffectsofplantbioactivecompoundsont47dbreastcancercellslineareview AT malizarita cytotoxiceffectsofplantbioactivecompoundsont47dbreastcancercellslineareview |